Is the corner of your mouth pulling south even when you feel fine? A carefully planned Botox strategy can relax the depressor muscles that tug the smile line downward, softening a sad or stern look without freezing your expression.
Why mouth corners turn down, even at rest
The mouth is a tug-of-war between elevators and depressors. Over time, the depressor anguli oris (DAO) muscles near the chin win that contest. They attach from the jawline area to the mouth corner and pull it down during frowning or certain speech patterns. Repetition, genetics, and bone changes with age can leave those corners tucked downward even when you are neutral. Add volume loss in the lateral cheek and marionette area and the lines deepen into folds. A few patients also develop compensatory overactivity in the chin, known as mentalis strain, which adds pebbled skin and a chin crease that amplifies the downturn.
Botox for downturned mouth targets the muscles that depress the corner, primarily the DAO, sometimes the depressor labii inferioris (DLI) and mentalis if their pull is adding to the appearance. The key is restraint. If you blunt the DAO just enough, the natural elevators, especially the zygomaticus muscles, regain the upper hand and the corner lifts a couple of millimeters. That small change reads as kinder, less tired, and more open.
A realistic result, measured in millimeters
Most patients see a 1 to 2 millimeter lift in the oral commissure. It does not erase marionette folds on its own, because those folds are structural. If you want a sharper edge and smoother fold, you often need a small amount of filler to support the corner after the DAO has relaxed. Think of Botox as changing the vector of pull, while filler changes the scaffolding. Together they can deliver a refined corner lift with natural movement.
Expect onset around day 5 to 7, with peak at day 10 to 14. Duration is usually 8 to 12 weeks for the mouth, shorter than the forehead because these muscles are active all day with speech and eating.
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Mapping the anatomy a provider must respect
A good injector studies how your mouth moves before marking any points. I ask patients to say “eee,” “ooo,” and “puppies,” then frown and smile gently. This helps locate the DAO’s active bands, which feel like slender cables just lateral to the corner of the mouth. The DLI sits more medially and pulls the lower lip down and out. The mentalis elevates and protrudes the central chin.
Why it matters: if the toxin diffuses into the DLI or the lower fibers of the orbicularis oris, you could get lip incompetence or difficulty holding a straw. If it drifts into the risorius or zygomaticus, the smile can look crooked. Precision is not optional, it is the whole game.
Technique choices that protect your smile
There are several ways to approach the DAO, and the choice depends on your anatomy and goals.
Microdroplet technique botox: This method uses ultrafine needle botox injections at very low dose, spaced like a constellation over the active DAO fibers. Each droplet might be 0.5 to 1 unit, placed superficially or just subdermal to keep the effect close to the target and limit spread. Microdroplets give exquisite control in a slim face or where the DAO straddles close to the risorius.
Tenting technique botox: In thicker skin or when the DAO saddles deeper, lifting the skin with a light pinch, then injecting into the created tent can keep the toxin from tracking along superficial planes. I reach for tenting when a patient has heavier tissue or when I am balancing asymmetry.
Classic paired-point injection patterns botox: The time-tested map places one point roughly 1 centimeter lateral and slightly inferior to the oral commissure over the DAO belly, and a second point slightly lower along the same vertical line. Doses range from 1 to 3 units per point per side. This works well in average anatomy but needs adjustment for short faces, wide jaws, or asymmetric smiles.
Needle vs cannula local botox injections Shelby Township botox: For neurotoxin, a needle is standard. Cannulas shine with fillers, not with Botox, because the DAO target is small and surface oriented. A 32 to 34 gauge ultrafine needle botox allows precise placement with minimal bruising.
Feathering: In patients worried about a frozen look, I prefer feathering botox technique, essentially microdroplets at the perimeter of the DAO activity. This preserves natural movement botox while softening the downward pull.
The first pass is intentionally conservative. It is safer to add 2 to 4 units at a two-week review than to overshoot on day one.
A clinic vignette from practice
A 46-year-old attorney came in with subtle downturn and a habit of tucking her lower lip when thinking. On animation, her left DAO was stronger than the right, and her chin dimpled with speech. We used microdroplet technique on the DAO, 5 units right, 7 units left, plus 4 units split bilaterally to the mentalis to quiet the pebbled surface. Two weeks later, the corners sat level, lift measured roughly 1.5 millimeters, and she reported fewer lipstick bleeds into early smoker’s lines. We later added 0.3 mL of hyaluronic acid to the lateral commissure for scaffolding. The sequence mattered: botox then filler timing allowed me to use less filler and avoid spreading product where the muscle pull had relaxed.
Dosing ranges and why body size is not the guide
DAO dosing typically ranges from 2 to 8 units per side. Petite patients with thin dermis may need as little as 1 to 2 units per point. Heavier tissue or a robust frown habit can push total dose to 10 units per side across two or three points. Body weight is not predictive, muscle activity is. Two people of similar build can have very different neuromuscular patterns shaped by speech, chewing preference, and stress.
If a patient clenches the jaw or grinds teeth, the masseter complex dominates. Treating jaw clenching with 20 to 40 units per side can indirectly soften the downturn by reducing strain across the lower face. It also refines the jawline in square jaw cases, aiding facial slimming and a gentle v shape face botox impression, though the intention is functional relief first.
Avoiding common pitfalls
Brow heaviness after botox and ptosis after botox get a lot of attention online, yet those complications come from upper-face dosing. The mouth has its own hazards. Over-relaxing the DLI yields a lower lip that doesn’t tuck properly, affecting enunciation of “f” and “v” sounds. Spillage into the orbicularis oris can worsen lip lines for a few weeks by unbalancing purse-string tone.
Asymmetric eyebrows botox is unrelated to mouth work, but asymmetry can occur at the corners if one DAO is dosed heavier than the other without reason. Your injector should test and mark asymmetry before loading the syringe.
Complication management botox for the lower face focuses on targeted reversals, not antidotes. Time is the antidote. Small imbalances can be corrected with microdosing the contralateral side or strengthening elevators through neuromuscular taping and massage. Severe speech or lip incompetence is rare with careful technique and conservative dosing, especially when using ultrafine needle botox to limit diffusion.

Pain free botox tips that do not blunt accuracy include ice for 30 seconds, a vibrating distraction device, and buffered reconstitution. Topical anesthetic is seldom necessary and can distort surface landmarks.
When Botox is not enough, or not the right tool
If the downturn is from volume collapse and tethered marionette ligaments, neurotoxin alone will not fix it. Layering botox with fillers can support the corner, fill the pre-jowl sulcus, and reduce the shadowing that reads as sad. I usually start with botox, wait two weeks, then add filler at micro-aliquots around the oral commissure and marionette line. Filler then botox timing makes sense only if you are correcting a large structural deficit first, but most cases benefit from relaxing the vector of pull before placing gel.
Smile lines botox alternatives include skin boosters and microneedling if surface crêpe is prominent. Botox with skin boosters can improve hydration and fine texture around the perioral area. Just keep units conservative to maintain an expressive face botox outcome. For deeper static lines, targeted hyaluronic acid or a light fractional laser pass does more than piling on toxin.
Botox for lip lines, smoker’s lines, and barcode lines botox must be feather-light to avoid a frozen look. Typically 2 to 6 units dispersed in microdroplets around the upper lip, combined with skincare like tretinoin or low-energy laser polishing, yields the best result. Botox for chin crease often complements DAO work since the chin and corner interact dynamically.
Special situations and adjacent indications
Many patients asking about downturned corners also ask about Botox for nose lines, nasal flare, or a gummy smile correction. Small doses to the levator labii superioris alaeque nasi can reduce a gummy smile and balance the upper lip with the newly lifted corners. Similarly, subtle dosing to soften bunny lines maintains harmony across the midface.
If you have hooded eyes or eyebrow asymmetry, resist the temptation to “fix everything at once” on the first visit. Watch how the mouth adjustment changes overall expressivity. Sometimes a tiny tweak to the crow’s feet or forehead with baby botox for crow’s feet or baby botox for forehead during a follow-up gives a coherent, natural movement botox outcome without tipping into a uniform, glassy look.
For patients with medical indications like hemifacial spasm or blepharospasm, a neurologist-led plan can coexist with aesthetic treatment, but sequencing and mapping must be coordinated. Spasticity programs, cervical dystonia, or shoulder pain protocols use higher total units and different dilution. Inform your aesthetic injector so they can account for baseline tone and prior dosing.
Choosing the right injector for mouth-corner work
The lower face is less forgiving than the forehead. How to find a good botox injector starts with reviewing their training and case mix. It helps to ask about botox injector credentials, such as board certification in dermatology, plastic surgery, facial plastic surgery, or a seasoned nurse practitioner or physician assistant with specific facial aesthetics training and supervision. Look for a botox injector portfolio that shows before-and-after images taken at consistent angles and lighting, ideally 2 weeks after treatment when effects peak. Scan botox injector reviews, but read critically for comments on natural movement and subtlety, not just “great service.”
Technique matters more than a brand name. Ask how they individualize botox injector technique, whether they use microdroplet technique botox for the DAO and how they prevent spread into the DLI. An experienced botox provider will discuss injection patterns botox and what adjustments they make for asymmetry, speech habits, or prior filler.
Finally, ask about complication management botox. A confident injector will explain how they avoid a frozen look botox result and how they would handle lip heaviness or asymmetry if it occurred.
What to expect during and after the appointment
Marking and dosing take longer than injecting. You will purse, smile, and frown several times as landmarks are mapped. I prefer patients sitting upright so gravity and tissue behavior match real life. The skin is cleaned thoroughly, then the DAO is injected with an ultrafine needle. A typical session for the lower face involves 4 to 16 units total and lasts about 10 minutes of actual injection time.
Immediately after, you will see tiny blebs that settle within 15 minutes and small red dots. Bruising is uncommon but possible, especially if you take fish oil, high-dose vitamin E, or NSAIDs. I advise avoiding massaging the area for the remainder of the day, vigorous exercise, or face-down massage. Normal speech and eating are fine. Full effect arrives by day 10 to 14.
A two-week review is not optional in my clinic. The mouth is a dynamic site. Small touch-ups create a much better long-term map of your personal response and help us maintain subtle botox movement rather than chasing results at three-month intervals.
Integrating lower-face Botox with skincare and procedures
The best lower-face results ride on healthy skin. A sound botox and tretinoin routine, at night on non-irritated days, helps smooth etched lines and improves collagen over months. Patients who like vitamin C serums can apply in the morning, followed by botox and sunscreen thinking, meaning diligent SPF use that protects your investment. Hyaluronic acid, niacinamide, and peptides skincare help with barrier and fine-line plumpness, especially around the perioral area.
If you want a resurfacing adjunct, Botox with microneedling or chemical peels can be sequenced safely. I schedule toxin first, wait one to two weeks, then resurface. Botox with laser treatments works similarly, as long as we avoid heat over fresh injection points for 24 to 48 hours to reduce diffusion risk. For exfoliation lovers, keep an easy botox and exfoliation schedule: pause strong exfoliants two days before and after injections to reduce irritation and bruising.
For sweat concerns that affect makeup wear and lower-face shine, there is growing interest in botox for facial sweating and redness control. Light dosing can quiet flushing in rosacea-prone cheeks and reduce sweat along the upper lip line, though that area demands microdosing for function. Topical botox alternatives and botox cream myth persist online, but current evidence supports injectables over topicals for reliable neuromodulation.
How lower-face work relates to the rest of the face and neck
A balanced face often needs gentle tweaks across zones. A DAO lift pairs well with a conservative Nefertiti lift botox in patients who show strong platysmal pull that exacerbates marionette folds. The neck bands can drag the jawline downward, so relaxing them can indirectly help the corners. For tech neck or chest lines, a mix of microbotox and skin treatments can improve texture, though those are separate goals from a commissure lift.
Patients who address jaw function with botox for shoulder pain caused by trapezius strain or for trapezius slimming sometimes notice a perceived lift in posture and a more open neckline. That change can make the lower face look more supported. Barbie botox trapezius remains a trend term, yet the medical use case is relief from tension headaches and shoulder tightness, with body-contour shifts as a secondary effect.
Outside the face, areas like palmar hyperhidrosis, plantar hyperhidrosis, and armpit odor respond well to neurotoxin and can improve everyday comfort. They are unrelated to mouth corners but show the treatment’s versatility, from overactive bladder and urinary incontinence to anal fissure spasm relief in specialist hands. I mention these because if you already receive medical botox, your aesthetic dosing plan must account for total units and timing to avoid stacking effects.
Setting expectations and maintaining the result
The lower face moves constantly with speech and eating, so results fade sooner than in the forehead. Many patients repeat DAO dosing every 8 to 12 weeks, extending to 12 to 16 weeks once muscles decondition. Light dose botox or baby dosing helps maintain subtlety in expressive faces. If you plan filler support, a touch every 9 to 18 months is typical, depending on product and metabolism.
Some tips enhance longevity. Avoid smoking, which accelerates perioral lines and undermines vascular supply. Address bruxism, since masseter overdrive stiffens the whole lower third. Skincare with retinoids and sunscreen, plus hydration and sleep, sound pedestrian, but they show up on your face faster than any gadget.
When not to treat
There are firm red lights. Pregnancy, breastfeeding, active skin infections, or neuromuscular disorders with compromised swallowing function are clear reasons to wait. Recent isotretinoin use is not a contraindication for toxin, but it matters for combined procedures. If you have an event requiring crisp enunciation and straw use, avoid first-time perioral botox in the 2 weeks prior. Trial dosing months ahead is smarter.
Patients seeking a dramatic corner lift from toxin alone are also poor candidates. If you pinch and lift the corner and need more than 2 millimeters to feel satisfied, you will likely need filler, skin tightening, or even surgical options like a corner lip lift in the right hands.
A short checklist for your consultation
- Ask about the provider’s DAO strategy: points, microdroplet use, and steps to avoid DLI spread. Review before-and-after photos focused on mouth corners, taken at 2-week follow-up. Discuss dose range for your anatomy and the plan for a two-week refinement visit. Clarify how filler might complement toxin and in what sequence. Confirm aftercare and how they handle asymmetry or unwanted heaviness.
A brief comparison: what changes right away, what needs support
- Botox relaxes the downward pull, usually lifting the corner modestly within two weeks. Filler supports marionette shadows and the commissure, improving contour instantly. Skin treatments refine surface lines over weeks to months, not structure. Habit shifts like bruxism management and speech awareness enhance durability. Skincare and sunscreen maintain texture, pigment, and collagen for the long run.
Final thought from the chair
A subtle lift at the corners is not about erasing movement, it is about returning balance to the vectors that sculpt your expression. When the DAO is calibrated rather than silenced, the elevators do what they were built to do, and your neutral face looks more like how you feel. Choose a botox injector who listens to how you speak, watches how you smile, and shows the humility to under-treat before they refine. The mouth will reward that restraint with a result that looks like you on a good day.